Science News: Dopamine Medication May Help with Sleep & Depression


Think of non-movement symptoms in Parkinson’s disease (PD) as fingerprints — everyone has them, but they’re different for every person. These symptoms can include depression, anxiety, problems sleeping and more. They often go under-reported and under-treated in people with Parkinson’s.

To help, some doctors prescribe a type of drug known as a Monoamine oxidase-B (MAO-B) inhibitor because of its ability to help make more dopamine available to the brain. These drugs can mildly improve some PD movement symptoms.

Surprisingly, there is not a lot of research that shows exactly how MAO-B inhibitors help non-movement symptoms. Parkinson’s Foundation National Medical Advisor Michael S. Okun, MD, co-authored a study analyzing a total of 60 MAO-B inhibitor studies and how they impact non-movement symptoms in Parkinson’s. Find out which symptoms improved, and which ones did not.

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